Professor Grant Collins
LOCATION
Room 214 PEMS North (Bldg 22) School of Physical, Environmental and Mathematical Sciences, UNSW Canberra, Australian Defence Force Academy, PO Box 7916, Canberra BC ACT 2610, AUSTRALIA
- PUBLICATIONS
Book Chapters
Collins JG; Smith JA; Li F; Keene FR, 2013, 'Noncovalent DNA binding of metal complexes', in Reedijk J; Poeppelmeier K (ed.), Comprehensive Inorganic Chemistry II, 2nd Edition, Elsevier, pp. 709 - 750, http://dx.doi.org/10.1016/B978-0-08-097774-4.00329-6
Day AI; Collins JG, 2012, 'Cucurbituril Receptors and Drug Delivery', in Gale PA; Steed JW (ed.), Supramolecular Chemistry: From Molecules to Nanomaterials, edn. Original, John Wiley & Sons, Chichester, UK, pp. 983 - 1000
Buck DP; Collins JG, 2011, 'NMR Studies of Metallointercalator-DNA Interactions', in AldrichWright J (ed.), METALLOINTERCALATORS: SYNTHESIS AND TECHNIQUES TO PROBE THEIR INTERACTIONS WITH BIOMOLECULES, SPRINGER-VERLAG WIEN, pp. 143 - 157, http://dx.doi.org/10.1007/978-3-211-99079-7_6
Hicks M; Orkey NU; Pisani M; Collins JG; Wheate NJ; Aldrich-Wright JR, 2011, 'Using spectroscopic techniques to examine drug-DNA interactions', in Wanunu M; Tor Y (ed.), Methods for Studying Nucleic Acid/Drug Interactions, CRC Press, pp. 3 - 42, http://www.amazon.com/Methods-Studying-Nucleic-Acid-Interactions/dp/1439839735/ref=sr_1_1?ie=UTF8&qid=1321669613&sr=8-1)
Buck DP; Collins JG, 2011, 'NMR Studies of Metallointercalator-DNA Interactions', in Aldrich Wright JR (ed.), Metallointercalators - Synthesis and Techniques to Probe Their Interactions with Biomolecules, edn. 1st, Springer, New York, pp. 143 - 157, http://dx.doi.org/10.1007/978-3-211-99079-7
Smith JA; Collins JG; Keene FR, 2009, 'Groove-binding ruthenium(II)complexes as probes of DNA recognition', in Hadjiliadis N; Sletten E (ed.), Metal Complex-DNA Interactions, edn. Original, Wiley, UK, pp. 319 - 346
Journal articles
Pumuye PP; Evison BJ; Konda SK; Collins JG; Kelso C; Medan J; Sleebs BE; Watson K; Phillips DR; Cutts SM, 2020, 'Formaldehyde-activated WEHI-150 induces DNA interstrand crosslinks with unique structural features', Bioorganic and Medicinal Chemistry, vol. 28, http://dx.doi.org/10.1016/j.bmc.2019.115260
Sun B; Sundaraneedi MK; Southam HM; Poole RK; Musgrave IF; Keene FR; Collins JG, 2019, 'Synthesis and biological properties of tetranuclear ruthenium complexes containing the bis[4(4′-methyl-2,2′-bipyridyl)]-1,7-heptane ligand', Dalton Transactions, vol. 48, pp. 14505 - 14515, http://dx.doi.org/10.1039/c9dt03221e
Flint KL; Collins JG; Bradley SJ; Smith TA; Sumby CJ; Keene FR, 2019, 'Synthesis and Characterisation of Helicate and Mesocate Forms of a Double-Stranded Diruthenium(II) Complex of a Di(terpyridine) Ligand', Australian Journal of Chemistry, vol. 72, pp. 762 - 768, http://dx.doi.org/10.1071/CH19220
Li X; Gorle AK; Sundaraneedi MK; Keene FR; Collins JG, 2018, 'Kinetically-inert polypyridylruthenium(II) complexes as therapeutic agents', Coordination Chemistry Reviews, vol. 375, pp. 134 - 147, http://dx.doi.org/10.1016/j.ccr.2017.11.011
Sun B; Musgrave IF; Day AI; Heimann K; Keene FR; Collins JG, 2018, 'Eukaryotic cell toxicity and HSA binding of [Ru(Me
Liu X; Sun B; Kell REM; Southam HM; Butler JA; Li X; Poole RK; Keene FR; Collins JG, 2018, 'The Antimicrobial Activity of Mononuclear Ruthenium(II) Complexes Containing the dppz Ligand', ChemPlusChem, vol. 83, pp. 643 - 650, http://dx.doi.org/10.1002/cplu.201800042
Sundaraneedi M; Eichenberger RM; Al-Hallaf R; Yang D; Sotillo J; Rajan S; Wangchuk P; Giacomin PR; Keene FR; Loukas A; Collins JG; Pearson MS, 2018, 'Polypyridylruthenium(II) complexes exert in vitro and in vivo nematocidal activity and show significant inhibition of parasite acetylcholinesterases', International Journal for Parasitology: Drugs and Drug Resistance, vol. 8, pp. 1 - 7, http://dx.doi.org/10.1016/j.ijpddr.2017.11.005
Sun B; Southam HM; Butler JA; Poole RK; Burgun A; Tarzia A; Keene FR; Collins JG, 2018, 'Synthesis, isomerisation and biological properties of mononuclear ruthenium complexes containing the bis[4(4′-methyl-2,2′-bipyridyl)]-1,7-heptane ligand', Dalton Transactions, vol. 47, pp. 2422 - 2434, http://dx.doi.org/10.1039/c7dt04595f
Sundaraneedi MK; Tedla BA; Eichenberger RM; Becker L; Pickering D; Smout MJ; Rajan S; Wangchuk P; Keene FR; Loukas A; Collins JG; Pearson MS, 2017, 'Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases', PLoS Neglected Tropical Diseases, vol. 11, http://dx.doi.org/10.1371/journal.pntd.0006134
Konda SK; Maliki R; McGrath S; Parker BS; Robinson T; Spurling A; Cheong A; Lock P; Pigram PJ; Phillips DR; Wallace L; Day AI; Collins JG; Cutts SM, 2017, 'Encapsulation of Mitoxantrone within Cucurbit[8]uril Decreases Toxicity and Enhances Survival in a Mouse Model of Cancer', ACS Medicinal Chemistry Letters, vol. 8, pp. 538 - 542, http://dx.doi.org/10.1021/acsmedchemlett.7b00090
Sundaraneedi MK; Ammit AJ; Tedla BA; Pearson MS; Loukas A; Keene FR; Collins JG, 2017, 'Tetranuclear Polypyridylruthenium(II) Complexes as Inhibitors and Down-Regulators of Phosphatase Enzymes', ChemistrySelect, vol. 2, pp. 10668 - 10672, http://dx.doi.org/10.1002/slct.201702118
Li F; Gorle AK; Ranson M; Vine KL; Kinobe R; Feterl M; Warner JM; Keene FR; Collins JG; Day AI, 2017, 'Probing the pharmacokinetics of cucurbit[7, 8 and 10]uril: And a dinuclear ruthenium antimicrobial complex encapsulated in cucurbit[10]uril', Organic and Biomolecular Chemistry, vol. 15, pp. 4172 - 4179, http://dx.doi.org/10.1039/c7ob00724h
Gorle AK; Bottomley AL; Harry EJ; Collins JG; Keene FR; Woodward CE, 2017, 'DNA condensation in live E. coli provides evidence for transertion', Molecular BioSystems, vol. 13, pp. 677 - 680, http://dx.doi.org/10.1039/c6mb00753h
Weber DK; Sani M-A; Downton MT; Separovic F; Keene FR; Collins JG, 2016, 'Membrane Insertion of a Dinuclear Polypyridylruthenium(II) Complex Revealed by Solid-State NMR and Molecular Dynamics Simulation: Implications for Selective Antibacterial Activity', Journal of the American Chemical Society, vol. 138, pp. 15267 - 15277, http://dx.doi.org/10.1021/jacs.6b09996
Gorle AK; Li X; Primrose S; Li F; Feterl M; Kinobe RT; Heimann K; Warner JM; Richard Keene F; Grant Collins J, 2016, 'Oligonuclear polypyridylruthenium(II) complexes: Selectivity between bacteria and eukaryotic cells', Journal of Antimicrobial Chemotherapy, vol. 71, pp. 1547 - 1555, http://dx.doi.org/10.1093/jac/dkw026
Li X; Heimann K; Dinh XT; Keene FR; Collins JG, 2016, 'Biological processing of dinuclear ruthenium complexes in eukaryotic cells', Molecular BioSystems, vol. 12, pp. 3032 - 3045, http://dx.doi.org/10.1039/c6mb00431h
Li X; Heimann K; Li F; Warner JM; Richard Keene F; Grant Collins J, 2016, 'Dinuclear ruthenium(II) complexes containing one inert metal centre and one coordinatively-labile metal centre: Syntheses and biological activities', Dalton Transactions, vol. 45, pp. 4017 - 4029, http://dx.doi.org/10.1039/c5dt04885k
Konda SK; Kelso C; Medan J; Sleebs BE; Phillips DR; Cutts SM; Collins JG, 2016, 'Isolation and structural analysis of the covalent adduct formed between a bis-amino mitoxantrone analogue and DNA: a pathway to major–minor groove cross-linked adducts', Org. Biomol. Chem., vol. 14, pp. 10217 - 10221, http://dx.doi.org/10.1039/C6OB02100J
Konda SK; Kelso C; Pumuye PP; Medan J; Sleebs BE; Cutts SM; Phillips DR; Collins G, 2016, 'Reversible and formaldehyde-mediated covalent binding of a bis-amino mitoxantrone analogue to DNA', Org. Biomol. Chem., vol. 14, pp. 4728 - 4738, http://dx.doi.org/10.1039/C6OB00561F
Gorle AK; Feterl M; Warner JM; Primrose S; Constantinoiu CC; Keene FR; Collins G, 2015, 'Mononuclear Polypyridylruthenium(II) Complexes with High Membrane Permeability in Gram-Negative Bacteria-in particular Pseudomonas aeruginosa', Chemistry (Weinheim an der Bergstrasse, Germany), vol. 21, pp. 10472 - 10481, http://dx.doi.org/10.1002/chem.201500385
Pandrala M; Sundaraneedi MK; Ammit AJ; Woodward CE; Wallace L; Keene FR; Collins G, 2015, 'Differential Anticancer Activities of the Geometric Isomers of Dinuclear Iridium(III) Complexes', European Journal of Inorganic Chemistry, vol. 2015, pp. 5694 - 5701, http://dx.doi.org/10.1002/ejic.201501069
Konda SK; Wang H; Cutts SM; Phillips DR; Collins JG, 2015, 'Binding of pixantrone to DNA at CpA dinucleotide sequences and bulge structures', Org. Biomol. Chem., vol. 13, pp. 5972 - 5982, http://dx.doi.org/10.1039/C5OB00526D
Li F; Collins JG; Keene FR, 2015, 'Ruthenium complexes as antimicrobial agents', Chem. Soc. Rev., vol. 44, pp. 2529 - 2542, http://dx.doi.org/10.1039/C4CS00343H
Li X; Gorle AK; Ainsworth TD; Heimann K; Woodward CE; collins J; Richard Keene F, 2015, 'RNA and DNA binding of inert oligonuclear ruthenium( ii ) complexes in live eukaryotic cells', Dalton Trans., vol. 44, pp. 3594 - 3603, http://dx.doi.org/10.1039/C4DT02575J
Upadhyay PJ; Zhou F; Collins G; Wheate NJ, 2014, 'TARGETED DELIVERY OF PLATINUM DRUGS TO TUMOURS USING CARRIER DNA-TETHERED APTAMERS', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, vol. 10, pp. 42 - 43, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100118&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Gorle AK; Feterl M; Warner JM; Wallace L; Keene FR; Collins JG, 2014, 'Tri- and tetra-nuclear polypyridyl ruthenium( ) complexes as antimicrobial agents', Dalton Trans., vol. 43, pp. 16713 - 16725, http://dx.doi.org/10.1039/C4DT02139H
Gorle AK; Ammit AJ; Wallace L; Keene FR; Collins JG, 2014, 'Multinuclear ruthenium( ) complexes as anticancer agents', New Journal of Chemistry, vol. 38, pp. 4049 - 4059, http://dx.doi.org/10.1039/C4NJ00545G
Li F; Harry EJ; Bottomley AL; Edstein MD; Birrell GW; Woodward CE; Keene FR; Collins JG, 2014, 'Dinuclear ruthenium(ii) antimicrobial agents that selectively target polysomes in vivo', Chemical Science, vol. 5, pp. 685 - 693, http://dx.doi.org/10.1039/c3sc52166d
Li F; Feterl M; Warner JM; Keene FR; Collins JG, 2013, 'Dinuclear polypyridylruthenium(II) complexes: flow cytometry studies of their accumulation in bacteria and the effect on the bacterial membrane', Journal of Antimicrobial Chemotherapy, vol. 68, pp. 2825 - 2833, http://dx.doi.org/10.1093/jac/dkt279
Pandrala M; Li F; Wallace L; Steel PJ; Moore B; Autschbach J; Collins JG; Keene FR, 2013, 'Iridium(iii) Complexes Containing 1,10-Phenanthroline and Derivatives: Synthetic, Stereochemical, and Structural Studies, and their Antimicrobial Activity', Australian Journal of Chemistry, vol. 66, pp. 1065 - 1073, http://dx.doi.org/10.1071/CH13264
Pandrala M; Li F; Feterl M; Mulyana Y; Warner JM; Wallace L; Keene FR; Collins JG, 2013, 'Chlorido-containing ruthenium(ii) and iridium(iii) complexes as antimicrobial agents', Journal of the Royal Chemical Society, Dalton Transactions, vol. 42, pp. 4686 - 4694, http://dx.doi.org/10.1039/c3dt32775b
Li F; Feterl M; Warner JM; Day AI; Keene FR; Collins JG, 2013, 'Protein binding by dinuclear polypyridyl ruthenium(ii) complexes and the effect of cucurbit[10]uril encapsulation', Journal of the Royal Chemical Society, Dalton Transactions, vol. 42, pp. 8868 - 8877, http://dx.doi.org/10.1039/c3dt50551k
Li F; Feterl M; Mulyana Y; Warner JM; Collins JG; Keene FR, 2012, 'In vitro susceptibility and cellular uptake for a new class of antimicrobial agents: Dinuclear ruthenium(II) complexes', Journal of Antimicrobial Chemotherapy, vol. 67, pp. 2686 - 2695, http://dx.doi.org/10.1093/jac/dks291
Ching HYV; Buck DP; Bhadbhade M; Collins JG; Rendina LM, 2012, 'A ternary supramolecular system containing a boronated DNAmetallointercalator, b-cyclodextrin and the hexanucleotide d(GTCGAC)', Chemical Communications, vol. 48, pp. 880 - 882, http://dx.doi.org/10.1039/c1cc15552k
Li F; Weber DK; Collins JG; Keene FR, 2012, 'An approach to therapeutic agents through selective targeting of destabilised nucleic acid duplex sequences', Journal of the Royal Chemical Society, Dalton Transactions, vol. 41, pp. 6528 - 6535, http://dx.doi.org/10.1039/c2dt12146h
Mulyana Y; Collins JG; Keene FR, 2011, 'Synthesis, nucleic acid binding and cytotoxicity of oligonuclear ruthenium complexes containing labile ligands', Journal of Inclusion Phenomena and Macrocyclic Chemistry, vol. 71, pp. 371 - 379, http://dx.doi.org/10.1007/s10847-011-0036-1
Mulyana Y; Weber DK; Buck DP; Motti CA; Collins JG; Keene FR, 2011, 'Oligonuclear polypyridylruthenium(ii) complexes incorporating flexible polar and non-polar bridges: Synthesis, DNA-binding and cytotoxicity', Journal of the Royal Chemical Society, Dalton Transactions, vol. 40, pp. 1510 - 1523, http://dx.doi.org/10.1039/c0dt01250e
Li F; Mulyana Y; Feterl M; Warner J; Collins JG; Keene FR, 2011, 'The antimicrobial activity of inert oligonuclear polypyridylruthenium(ii) complexes against pathogenic bacteria, including MRSA', Journal of the Royal Chemical Society, Dalton Transactions, vol. 40, pp. 5032 - 5038, http://dx.doi.org/10.1039/c1dt10250h
Pisani M; Fromm P; Mulyana Y; Clarke RA; Korner H; Heimann K; Collins JG; Keene FR, 2011, 'Mechanism of cytotoxicity and cellular uptake of lipophilic inert dinuclear polypyridylruthenium(II) complexes', Chemmedchem, vol. 6, pp. 848 - 858, http://dx.doi.org/10.1002/cmdc.201100053
Buck DP; Paul JA; Pisani M; Collins JG; Keene FR, 2010, 'Binding of a Flexibly-linked Dinuclear Ruthenium(II)', Australian Journal of Chemistry, vol. 63, pp. 1365 - 1375, http://dx.doi.org/10.1071/CH10065
Pisani M; Weber DK; Heimann K; Collins JG; Keene FR, 2010, 'Selective mitochondrial accumulation of cytotoxic dinuclear polypyridyl rutheniunm(II) complexes', Metallomics, vol. 2, pp. 393 - 396, http://dx.doi.org/10.1039/c004922k
Mansour OC; Evison BJ; Sleebs BE; Watson KG; Nudelman A; Rephaeli A; Buck DP; Collins JG; Bilardi RA; Phillips DR; Cutts SM, 2010, 'New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation', Journal of Medicinal Chemistry, vol. 53, pp. 6851 - 6866, http://dx.doi.org/10.1021/jm901894c
Adnan N; Buck DP; Evison B; Cutts SM; Phillips DR; Collins JG, 2010, 'DNA binding by pixantrone', Organic and Biomolecular Chemistry, vol. 8, pp. 5359 - 5366, http://dx.doi.org/10.1039/C0OB00295J
Pisani M; Zhao Y; Wallace L; Woodward CE; Keene FR; Day AI; Collins JG, 2010, 'Cucurbit[10]uril binding of dinuclear platinum(II) and ruthenium(II) complexes: association/dissociation rates from seconds to hours', Journal of the Royal Chemical Society, Dalton Transactions, vol. 39, pp. 2078 - 2086, http://dx.doi.org/10.1039/b921172a
